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Publikationen

Publikationen

2021

Wolff, H., Kunz, A. Hirnorganoide – Ethische Herausforderungen und ihre Berücksichtigung und Umsetzung im Recht.MedR 39, 800–808 (2021) https://doi.org/10.1007/s00350-021-5977-9 

Falk, S., Han, D., & Karow, M. (2021). Cellular identity through the lens of direct lineage reprogramming. Current Opinion in Genetics & Development70, 97-103. https://doi.org/10.1016/j.gde.2021.06.015 

Triebelhorn, J., Kuffner, K., Cardon, I., Meindl, K., Rothhammer-Hampl, T., Riemenschneider, M. J., ... & Wetzel, C. H. (2021). Induced neural progenitor cells and iPS-neurons from major depressive disorder patients show altered bioenergetics and electrophysiological properties. bioRxivhttps://doi.org/10.1101/2021.04.30.441774 

Rothhammer-Hampl, T., Liesenberg, F., Hansen, N., Hoja, S., Delic, S., Reifenberger, G., & Riemenschneider, M. J. (2021). Frequent Epigenetic Inactivation of DIRAS-1 and DIRAS-2 Contributes to Chemo-Resistance in Gliomas. Cancers13(20), 5113.  https://doi.org/10.3390/cancers13205113

Mészáros, L., Riemenschneider, M. J., Gassner, H., Marxreiter, F., von Hörsten, S., Hoffmann, A., & Winkler, J. (2021). Human alpha-synuclein overexpressing MBP29 mice mimic functional and structural hallmarks of the cerebellar subtype of multiple system atrophy. Acta neuropathologica communications9(1), 1-16.  https://doi.org/10.1186/s40478-021-01166-x 

Fischer, D. S., Dony, L., König, M., Moeed, A., Zappia, L., Heumos, L., ... & Theis, F. J. (2021). Sfaira accelerates data and model reuse in single cell genomics. Genome biology22(1), 1-21. https://doi.org/10.1186/s13059-021-02452-6 

Fischer, D. S., Schaar, A. C., & Theis, F. J. (2021). Learning cell communication from spatial graphs of cells. bioRxivhttps://doi.org/10.1101/2021.07.11.451750 

Zunke, F., Winner, B., Richter, F., & Caraveo, G. (2021). Intracellular Mechanisms of α-Synuclein processing. Frontiers in Cell and Developmental Biology, 2493. doi: 10.3389/fcell.2021.752378 

Günther, C., Rothhammer, V., Karow, M., Neurath, M. F., & Winner, B. (2021). The Gut-Brain Axis in Inflammatory Bowel Disease—Current and Future  Perspectives. International Journal of Molecular Sciences22(16), 8870. https://doi.org/10.3390/ijms22168870

Krumm, L., Pozner, T., Kaindl, J., Regensburger, M., Günther, C., Turan, S., ... & Winner, B. (2021). Generation and characterization of an endogenously tagged SPG11-human iPSC line by CRISPR/Cas9 mediated knock-in. Stem Cell Research56, 102520.https://doi.org/10.1016/j.scr.2021.102520

Mészáros, L., Riemenschneider, M. J., Gassner, H., Marxreiter, F., von Hörsten, S., Hoffmann, A., & Winkler, J. (2021). Human alpha-synuclein overexpressing MBP29 mice mimic functional and structural hallmarks of the cerebellar subtype of multiple system atrophy. Acta neuropathologica communications9(1), 1-16. https://doi.org/10.1186/s40478-021-01166-x

Güner, F., Pozner, T., Krach, F., Prots, I., Loskarn, S., Schlötzer-Schrehardt, U., ... & Regensburger, M. (2021). Axon-Specific Mitochondrial Pathology in SPG11 Alpha Motor Neurons. Frontiers in Neuroscience15, 843.https://doi.org/10.3389/fnins.2021.680572

Wittmann, M. T., Katada, S., Sock, E., Kirchner, P., Ekici, A. B., Wegner, M., ... & Reis, A. (2021). scRNA sequencing uncovers a TCF4-dependent transcription factor network regulating commissure development in mouse. Development148(14), dev196022. https://journals.biologists.com/dev/article-lookup/doi/10.1242/dev.196022

Mészáros L, Riemenschneider MJ, Gassner H, Marxreiter F, von Hörsten S, Hoffmann A, et al. Human alpha-synuclein overexpressing MBP29 mice mimic functional and structural hallmarks of the cerebellar subtype of multiple system atrophy. Acta Neuropathol Commun. 2021;9(1):68. https://doi.org/10.1186/s40478-021-01166-x 

 

2020

Boerstler, T., Wend, H., Krumbiegel, M., Kavyanifar, A., Reis, A., Lie, D. C., Winner, B., & Turan, S. (2020). CRISPR/Cas9 mediated generation of human ARID1B heterozygous knockout hESC lines to model Coffin-Siris syndrome. Stem cell research, 47. doi.org/10.1016/j.scr.2020.101889

Krach, F., Bogiongko, M. E., & Winner, B. (2020). Decoding Parkinson's disease - iPSC-derived models in the OMICs era. Molecular and cellular neurosciences, 106, 103501. doi.org/10.1016/j.mcn.2020.103501

Pozner, T., Regensburger, M., Engelhorn, T., Winkler, J., & Winner, B. (2020). Janus-faced spatacsin (SPG11): involvement in neurodevelopment and multisystem neurodegeneration. Brain : a journal of neurology, 143(8), 2369–2379. doi.org/10.1093/brain/awaa099

Simmnacher, K., Lanfer, J., Rizo, T., Kaindl, J., & Winner, B. (2020). Modeling Cell-Cell Interactions in Parkinson's Disease Using Human Stem Cell-Based Models. Frontiers in cellular neuroscience, 13, 571. doi.org/10.3389/fncel.2019.00571

Lambrecht, V., Hanspach, J., Hoffmann, A., Seyler, L., Mennecke, A., Straub, S., . . . Winkler, J. (2020). Quantitative susceptibility mapping depicts severe myelin deficit and iron deposition in a transgenic model of multiple system atrophy. Exp Neurol, 329, 113314. doi:10.1016/j.expneurol.2020.113314

Wedel, M., Frob, F., Elsesser, O., Wittmann, M. T., Lie, D. C., Reis, A., & Wegner, M. (2020). Transcription factor Tcf4 is the preferred heterodimerization partner for Olig2 in oligodendrocytes and required for differentiation. Nucleic Acids Res, 48(9), 4839-4857. doi:10.1093/nar/gkaa218

 

2019

Turan, S., Boerstler, T., Kavyanifar, A., Loskarn, S., Reis, A., Winner, B., & Lie, D. C. (2019). A novel human stem cell model for Coffin-Siris syndrome-like syndrome reveals the importance of SOX11 dosage for neuronal differentiation and survival. Hum Mol Genet, 28(15), 2589-2599. doi:10.1093/hmg/ddz089

Kaindl, J., & Winner, B. (2019). Disease Modeling of Neuropsychiatric Brain Disorders Using Human Stem Cell-Based Neural Models. Current topics in behavioral neurosciences, 42, 159–183. doi.org/10.1007/7854_2019_111

Turan, S., Boerstler, T., Kavyanifar, A., Loskarn, S., Reis, A., Winner, B., & Lie, D. C. (2019). A novel human stem cell model for Coffin-Siris syndrome-like syndrome reveals the importance of SOX11 dosage for neuronal differentiation and survival. Human molecular genetics, 28(15), 2589–2599. doi.org/10.1093/hmg/ddz089